The project is structured into the following work packages, WP:

WP I, Responsible researcher: G. Aldica

Physico-chemical characterization of MgB₂ powders and of other raw materials (additives, adhesives, others)

WP II, Responsible researcher: M.C. Chifiriuc

In vitro bioevaluation of materials from WP I

WP III, Responsible researcher: G. Aldica

Fabrication of bulk samples of MgB₂ with and without additives

WP IV, Responsible researcher: D. Batalu

Physico-chemico-mechanical-degradable characterization of bulks obtained at WP III

WP V, Responsible researcher: C. Bleotu

In vitro and in vivo bioevaluation of materials from previous WP (biocompatibility, microbicidal and anti-biofilm properties

WP VI Responsible researcher: D. Batalu

Powders and coatings for applications (powder+additive+liquid carrier & adhesive + propellant) with MgB₂ or other powder/coated medical devices/applications). Composite polymer-MgB₂ wires for 3D printing

WP VII Responsible researcher: A. Agostino

MgB₂ bulks for applications

WP VIII Responsible researcher: P. Badica, M. Truccato

The project management and dissemination of the scientific results

ITALY

Under construction

The end of the project was extended to July 31, 2021.

see Romanian website https://infim.ro/project/biomb/

BSc:

1. Bunescu Anamaria (supervisor Batalu Dan, UPB): Technology for obtaining a polymeric composite for 3D printing (2018).

2. Copoiu Ștefan (supervisor Batalu Dan, UPB): Use of auxetic materials in medical engineering (2018).

3. Modiga Aida Andrada (supervisor Batalu Dan, UPB): Studies on the design of corneal implants (2018).

4. O Cristea (supervisor I Gheorghe, UB): Characterization of filamentous microscopic fungal strains isolated from lovrin wheat caryopsis (2019);

5. Andrei Cosmin Roznov (supervisor D Batalu): Study on digital processing and the use of PMMA in 3D printing with applications in dentistry (2019);

6. Roxana Georgiana Saveli (supervisor D Batalu): Design of a robotic finger (2019).

MSc:

1. M Lupsa (supervisor MC Chifiriuc, UB): Aspects regarding the virulence and antibiotic resistance of some microbial strains involved in oral pathology (2019);

2. DS Copoiu (coordonator MC Chifiriuc, UB): The microbial activity of nanoparticles on some species of filamentous fungi isolated from cultural heritage objects (2019);

3. Octavia Emilia Zetu (supervisor Irina Gheorghe, UB), Biodiversity of filamentous microscopic fungi involved in the process of biodeterioration of stone cultural heritage objects and new strategies for their preservation and restoration (2020)

4. Andreea Dumbrava (supervisor Irina Gheorghe), Complex analysis of filamentous microscopic fungal strains involved in the biodeterioration of wooden heritage churches in Arad, Hunedoara and Bucharest counties (2020)

5. Bunescu Anamaria (supervisor D. Batalu, UPB), Advanced design through topological optimization and 3D printing with applications in the aeronautical industry (2020).

PhD:

1. Othman Thamer Al-mahdawy (supervisor MC Chifiriuc, UB) Virulence and resistance markers in Gram-positive cocci of clinical importance (2019);

Journals

1. P. Badica, D. Batalu, M. Burdusel, M.A. Grigoroscuta, G. V. Aldica, M. Enculescu, R.A. Gabor, Z. Wang, R. Huang, P. Li, Compressive properties of pristine and SiC-Te-added MgB2 powders, green compacts, and Spark Plasma Sintered bulks, Ceram. Int. 44 (2018) 10181-10191 (doi:10.1016/j.ceramint.2018.03.008)

2. D. Batalu, F. Nastase, M. Militaru, M. Gherghiceanu, P. Badica, NiTi coated with oxide and polymer films in the in vivo healing processes, 2018, in press (doi: https://doi.org/10.1016/j.jmrt.2018.06.015)

3. Laura Gozzelino, Roberto Gerbaldo, Gianluca Ghigo, Daniele Torsello, Valentina Bonino, Marco Truccato, Mihai A Grigoroscuta, Mihail Burdusel, Gheorghe V Aldica, Viorel Sandu, Iuliana Pasuk, Petre Badica, High magnetic shielding properties of an MgB2 cup obtained by machining a spark-plasma-sintered bulk cylinder, SUST 33 (2020) 044018 (https://doi.org/10.1088/1361-6668/ab7846).

4. M. A. Grigoroscuta, G. Aldica, I. Pasuk, M. Burdusel, V. Sandu, A. Kuncser, T.S. Suzuki, O. Vasylkiv, P. Badica, Partially-oriented MgB2 superconducting bulks with addition of B4C and cubic BN obtained by slip casting under high magnetic field and spark plasma sintering, Mater. Res. Bull. 134 (2021) 111103 (https://doi.org/10.1016/j.materresbull.2020.111103).

5. M. A. Grigoroscuta, V. Sandu, A. Kuncser, I. Pasuk, G. Aldica, T.S. Suzuki, O. Vasylkiv, P. Badica, Superconducting MgB2 textured bulk obtained by ex situ spark plasma sintering from green compacts processed by slip casting under a 12T magnetic field, SUST 32 (2019) 125001 (https://doi.org/10.1088/1361-6668/ab4620).

6. Frone AN, Batalu D, Chiulan I, Oprea M, Gabor AR, Nicolae CA, Raditoiu V, Trusca R, Panaitescu DM, Morpho-Structural, Thermal and Mechanical Properties of PLA/PHB/Cellulose Biodegradable Nanocomposites Obtained by Compression Molding, Extrusion, and 3D Printing. NANOMATERIALS 10 (2020) 51 (doi: 10.3390/nano10010051).

7. Irina Gheorghe, Ionela Avram, Viorica Matis Corbu, Luminita Măruțescu, Marcela Popa, Irina Balotescu, Ion Blăjan, Venus Mateescu, Andreea Ștefania Dumbravă, Octavia Emilia Zetu, Ionut Pecete, Violeta Corina Cristea, Dan Nicolae Batalu, Mihai Alexandru Grigoroscuta, Mihail Burdusel, Gheorghe Virgil Aldica, Petre Badica, Adina Daniela Datcu, Nicoleta Ianovici, Coralia Bleotu, Veronica Lazar, Lia Mara Dițu, Mariana Carmen Chifiriuc, In vitro evaluation of MgB2 powders as novel tools to fight fungal biodeterioration of heritage buildings and objects, submitted

8. P. Badica, N.D. Batalu, M.C. Chifiriuc, M. Burdusel, M.A. Grigoroscuta, G. Aldica, I. Pasuk, A. Kuncser, M. Enculescu, M. Popa, L.G. Marutescu, I. Gheorghe, O. Thamer, C. Bleotu, G. Gradisteanu Pircalabioru, L. Operti, V. Bonino, A. Agostino, M. Truccato, Promising new inorganic materials to approach old medical challenges: bioevaluation of MgB2 powders interaction with planktonic microbes, biofilms and tumor cells, submitted

9. P. Badica, N.D. Batalu, M. Burdusel, M.A. Grigoroscuta, G. Aldica, M. Enculescu, G. Gradisteanu Pircalabioru, M. Popa, L.G. Marutescu, B.G. Dumitriu, L. Olariu, A. Bicu, B. Purcareanu, L. Operti, V. Bonino, A. Agostino, M. Truccato, and M.C. Chifiriuc, In vitro assay of the MgB2 powders cytocompatibility and antibacterial activity of MgB2-PVP biodegradable self-replenishing coatings against bacteria in planktonic and biofilm growth state, submitted.

Book chapters

1. Tribot, D. Batalu, C. Brasselet, C. Delattre, L. Wei, J. Lao, P. Badica, P. Michaud, H. de Baynast. Green polymers filaments for 3D printing, book chapter, Springer (accepted, to be published in 2021).

Patents:

1. P. Badica, D. Batalu, M. A. Grigoroscuta, M. Burdusel, G. V. Aldica, M. Popa, M. C. Chifiriuc, “Pulberi, corpuri sinterizate și acoperiri pe bază de MgB₂ rezistente la colonizarea microbiană și cu eficiență împotriva biofilmelor microbiene și metodă de folosire a acestora”, cerere brevet OSIM, A 2018 01129 (20.12.2018)

2. D.N. Batalu, A. Bunescu, P. Badica, Material compozit functional cu matrice din polimer si adaos de pulbere MgB₂, cerere brevet OSIM A 2020 00405 (15.07.2020)

Conferences:

2017

(1) D. Batalu, F. Nastase, M. Militaru, M. Gherghiceanu, L. Moldovan, M. Bucur, G. Aldica, P. Badica, New materials and devices for biomedical applications, International Union of Materials Research Societies - The 15^th International Conference on Advanced Materials (IUMRS-ICAM), August 27-September 1, 2017, Kyoto, Japonia (invited).

2018

(1) Alina Sîrghi, Irina Gheorghe, Luminița Marutescu, Dan Batalu, Petre Badica, Badea Mihaela, Rodica Olar, Omar Sadik, Gyath Aldin Aziz, Ionela Avram, Zhiyong Zong, Mariana Carmen Chifiric, Activity of different inorganic nanoparticles against fungal isolates colonising buildings included in the Romanian National Heritage, First Balkan Conference of Medical Mycology and Mycotoxicology – Balkan Fungus 2018, Timisoara, Romania, 13-15 September 2018 (oral).

(2) Othman Thamer Almahdawy, Petre Badica, Dan Batalu, Irina Gheorghe, Marcela Popa, Omar Sadik Shalal, Dunya Alkurjia, Otilia Banu, Luminita Marutescu, Grigore Mihaescu, Carmen Chifiriuc, In vitro activity of novel inorganic nanoparticles based on halogenatedmagnesium salts on MRSA cells in planktonic and adherent growth state, P2188. 22^th ECCMID, 24-28 April, Madrid, Spain (poster).

(3) D. Batalu, A. Bunescu, P. Badica, Assessment of some new polymeric composites used for 3D printing, 18^th European Conference on Composite Materials, Athens, Greece, June 24- 28, 2018 (poster).

(4) D. Batalu, A. Bunescu, M. Popa (Bucur), L. Marutescu, M.C. Chifiriuc, P. Badica, Assessment of Antibacterial Behavior of some Polymer Composites used for 3D printing, 4^th International Conference on Biomedical Polymers & Polymeric Biomaterials, Krakow, Poland, July 15- 18, 2018 (poster).

(5) N. Pons, A. Bunescu, P. Badica, D. Batalu, New Polymeric Composite for 3D printing, 14^th International Symposium PRIOCHEM, Bucharest, Romania, October 10-12, 2018 (poster).

2019

(1) P Badica, MgB₂-based materials for different applications, VI International Conference of Technical Chemistry from Theory to Praxis, 21-23 May 2019, Perm, Russia (invitata)

(2) P Badica, M Burdusel, MA Grigoroscuta, G Aldica, DN Batalu, M Bucur, C Chifiriuc, MgB₂ based materials for the improvement of life quality, 2^nd European ONE HEALTH Conference, 21-22 Iunie 2019, Bucuresti, Romania (oral)

(3) D Batalu, A Bunescu, P Badica, Z Xiang, W Lu, New composites for additive manufacturing, The 10^th Pacific Rim International Conference on Advanced Materials and Procesing (PRICM 10) 18-22 Aug 2019, Xi’an, China (oral)

(4) GV Aldica, D Batalu, P Badica, Thermal analysis on Ga or In acetylacetonate powders, 5^th Central and Eastern European Conference on Thermal Analysis and Calorimetry & 14^-th Mediterranean Conference on Calorimetry and Thermal Analysis, 27-30 Aug 2019, Roma, Italy (poster)

(5) OT Almahdawy, P  Badica, D Batalu, I Gheorghe, M Popa, O Sadik Shalal, D Alkurjia, O Banu, L Măruţescu, G Mihăescu, C Chifiriuc. In vitro activity of novel inorganic nanoparticlesbased on halogenated magnesium salts on MRSA cells in planktonic and adherent growth state, 28th European Congress of Clinical Microbiology and Infectious Diseases, 21-24.04.2018, Madrid, Spania (Poster).

2020

1. O serie de conferinte internationale/nationale planificate in 2020 au fost anulate sau amanate pentru 2021.

2. Viorica Corbu, Irina Gheorghe, Luminita Măruțescu, Marcela Popa, Irina Balotescu, Ion Blăjan, Venus Mateescu, Andreea Dumbravă, Octavia Zetu, Ionut Pecete, Violeta Cristea, Dan Batalu, Petre Badica, Nicoleta Ianovici, Coralia Bleotu, Veronica Lazar, Lia Mara Dițu, Carmen Chifiriuc. Activitatea antimicrobiană a nanoparticulelor de MgB2 asupra unor microfungi izolați de pe obiecte de patrimoniu cultural. Sesiunea de Comunicări Ştiințifice „D. Brandza” Ediția a-XXVI-^a (oral).

Visits

1. P. Badica delivered at Torino University two presentations:

(a) State of the art in the project ERA-M 74/2017 BIOMB

(b) Advanced biodegradable materials based on MgB₂ resistant to microbial colonization (2018)

2. P. Badica visited Torino University: experiments were performed for the synthesis and characterization of materials in the Mg-B system (2019).

3. The visit of the student Nicoletta Baglieri from Univ. from Turin to Bucharest (ERASMUS ++ scholarship) was canceled due to the COVID-19 pandemic (2020).

4. D. Batalu – visit to the company Recond Expert SRL, Baia Mare, 19-23 februarie (2020).